Birth of George to parents, Vincent and Natalina in Valletta, the capital city of Malta.

Starts attending the Lyceum Valletta. In 1896 begins studies philosophy and theology in preparation for the priesthood at the seminary.

While a deacon, Fr Preca begins meeting a group of young adults in front of the church of St Gaetan in Ħamrun. Following a two-year break, he meets up with them again on a daily basis for faith formation and selects Eugene Borg to lead the group.

Diagnosed suffering from tuberculosis by Professor Enrico Meli. The prognosis is a few months of life. Fr Preca miraculously recovers by December and survived with a damaged lung for 56 years.

George is ordained a diocesan priest at St John Co-Cathedral in Valletta.